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KMID : 0882419960500030405
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Korean Journal of Medicine
1996 Volume.50 No. 3 p.405 ~ p.409
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A Case of Islet Cell Hyperplasia of Pancreas Presenting as Hyperinsulinemic Hypoglycemia
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임석아
이순남/경난호/박응범/서정수/한운섭
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Abstract
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Islet cell hyperplasia is a common cause of persistent hyperinsulinemic hypoglycemia in pediatric population, but is very rare in adults. We experienced 64-year-old woman with history of symptomatic hypoglycemia such as ligh-headedness and loss
of
consciousness. Her blood glucose level measured in the emergency room after this incident, was 33mg/dl and documented elevation of her fasting plasma insulin to glucose ratio(0.76).
She responded to intravenous glucose administration. She was performed preoperative percutaneous transhepatic portal venous insulin sampling at 2cm intervals along the portal and splenic veins. Insulin levels at these sited were measured and
localization of oversecretion of insulin preoperatively and the patient underwent a distal pancreatectomy, which revealed islet cell hyperplasia only without definite mass. She remains asymptomatic 4 years after surgery with normal blood glucose
and
insulin level.
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KEYWORD
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